Infected-cell protein 0 (ICP0) is a RING finger E3 ligase that regulates herpes simplex virus (HSV) mRNA synthesis. and strongly influences the balance between latency and replication of HSV. For 25 years. the nuclear functions of ICP0 have been the subject of intense scrutiny. https://www.roneverhart.com/MagnaFlow-2007-2008-Mitsubishi-Outlander-OEM-Grade-Federal-EPA-Compliant-Manifold-Catalytic-Converter/