Objective: Colorectal cancer (CRC) is a prevalent malignant tumor with a high fatality rate. CircPDIA4 has been shown to have a vital role in cancer development by acting as a facilitator. Nevertheless. the impact of the circPDIA4/miR-9-5p/SP1 axis on development of CRC has not been studied. https://parisnaturalfoodes.shop/product-category/3-in-1-lavender/